pentobarbital will decrease the level or outcome of prednisone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.pentobarbital raises toxicity of ifosfamide by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor. CYP3A4 inducers may increase the metabolism of ifosfamide to its Lively alkylating met… Read More